Myeloid-derived miR-6236 potentiates adipocyte insulin signaling and prevents hyperglycemia during o...
Myeloid-derived miR-6236 potentiates adipocyte insulin signaling and prevents hyperglycemia during obesity
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Adipose tissue macrophages (ATMs) influence obesity-associated metabolic dysfunction, but the mechanisms by which they do so are not well understood. We show that miR-6236 is a bona fide miRNA that is secreted by ATMs during obesity. Global or myeloid cell-specific deletion of miR-6236 aggravates obesity-associated adipose tissue insulin resistance...
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Full title
Myeloid-derived miR-6236 potentiates adipocyte insulin signaling and prevents hyperglycemia during obesity
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TN_cdi_doaj_primary_oai_doaj_org_article_c8f82a79f5c0480ab908f0500c2bbc29
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8f82a79f5c0480ab908f0500c2bbc29
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-49632-z
