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Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates Aβ accumu...

Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates Aβ accumu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8fa582bf87b4ad3b667480aec09e9c9

Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates Aβ accumulation

About this item

Full title

Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates Aβ accumulation

Publisher

England: BMC

Journal title

Acta neuropathologica communications, 2025-03, Vol.13 (1), p.51-18, Article 51

Language

English

Formats

Publication information

Publisher

England: BMC

More information

Scope and Contents

Contents

Multiple lines of evidence indicate that immune signaling can impact the pathological progression in Alzheimer’s disease (AD), including amyloid deposition, tau aggregation, synaptic pathology and neurodegenerative trajectory. In earlier studies, we reported that intracerebral expression of the anti-inflammatory cytokines, Interleukin-10 (Il10) and...

Alternative Titles

Full title

Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates Aβ accumulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c8fa582bf87b4ad3b667480aec09e9c9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8fa582bf87b4ad3b667480aec09e9c9

Other Identifiers

ISSN

2051-5960

E-ISSN

2051-5960

DOI

10.1186/s40478-025-01968-3

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