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Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes

Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c901153a0f93424598e6b1d1ec7d9eba

Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes

About this item

Full title

Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-10, Vol.10 (1), p.4491-12, Article 4491

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Maintaining long-term euglycemia after intraportal islet transplantation is hampered by the considerable islet loss in the peri-transplant period attributed to inflammation, ischemia and poor angiogenesis. Here, we show that viable and functional islet organoids can be successfully generated from dissociated islet cells (ICs) and human amniotic epi...

Alternative Titles

Full title

Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c901153a0f93424598e6b1d1ec7d9eba

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c901153a0f93424598e6b1d1ec7d9eba

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-12472-3

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