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Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization

Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c9184b94467c470fae4a1a2e1c6345e2

Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization

About this item

Full title

Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization

Publisher

England: BioMed Central

Journal title

Journal of translational medicine, 2019-09, Vol.17 (1), p.321-321, Article 321

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Medulloblastoma (MB), the most common pediatric brain cancer, presents with a poor prognosis in a subset of patients with high risk disease, or at recurrence, where current therapies are ineffective. Cord blood (CB) natural killer (NK) cells may be promising off-the-shelf effector cells for immunotherapy due to their recognition of malignant cells...

Alternative Titles

Full title

Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c9184b94467c470fae4a1a2e1c6345e2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c9184b94467c470fae4a1a2e1c6345e2

Other Identifiers

ISSN

1479-5876

E-ISSN

1479-5876

DOI

10.1186/s12967-019-2055-4

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