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Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics

Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c91a73658de949548aa1a6962b0fe8cd

Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics

About this item

Full title

Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-04, Vol.11 (1), p.1786-1786, Article 1786

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Protein-protein interactions featuring intricate binding epitopes remain challenging targets for synthetic inhibitors. Interactions of NEMO, a scaffolding protein central to NF-κB signaling, exemplify this challenge. Various regulators are known to interact with different coiled coil regions of NEMO, but the topological complexity of this protein h...

Alternative Titles

Full title

Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c91a73658de949548aa1a6962b0fe8cd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c91a73658de949548aa1a6962b0fe8cd

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-15576-3

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