E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facili...
E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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E2F1 and retinoblastoma (RB) tumor-suppressor protein not only regulate the periodic expression of genes important for cell proliferation, but also localize to DNA double-strand breaks (DSBs) to promote repair. E2F1 is acetylated in response to DNA damage but the role this plays in DNA repair is unknown. Here we demonstrate that E2F1 acetylation cr...
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E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair
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TN_cdi_doaj_primary_oai_doaj_org_article_c922be47af0c487c9f56067db1a6901f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c922be47af0c487c9f56067db1a6901f
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12861-8
