USP39/SMC4 promotes hepatoma cell proliferation and 5-FU resistance
USP39/SMC4 promotes hepatoma cell proliferation and 5-FU resistance
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Author / Creator
Zhou, Bo , Li, Jie , Wu, Shuai , Zhang, Haomiao , Luo, Yuanbo , Chen, Jingxiang and Chen, Geng
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality, characterized by a high rate of postoperative recurrence and poor long-term survival outcomes. Structural maintenance of chromosome 4 (SMC4) is frequently overexpressed in various types of cancer and plays a pivotal role in tumor cell growth, migration, and invasion. Bio...
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Full title
USP39/SMC4 promotes hepatoma cell proliferation and 5-FU resistance
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c951bc5a78b04ed08dee7924516c5e90
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c951bc5a78b04ed08dee7924516c5e90
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-025-93029-x