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USP39/SMC4 promotes hepatoma cell proliferation and 5-FU resistance

USP39/SMC4 promotes hepatoma cell proliferation and 5-FU resistance

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c951bc5a78b04ed08dee7924516c5e90

USP39/SMC4 promotes hepatoma cell proliferation and 5-FU resistance

About this item

Full title

USP39/SMC4 promotes hepatoma cell proliferation and 5-FU resistance

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2025-03, Vol.15 (1), p.8869-13, Article 8869

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality, characterized by a high rate of postoperative recurrence and poor long-term survival outcomes. Structural maintenance of chromosome 4 (SMC4) is frequently overexpressed in various types of cancer and plays a pivotal role in tumor cell growth, migration, and invasion. Bio...

Alternative Titles

Full title

USP39/SMC4 promotes hepatoma cell proliferation and 5-FU resistance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c951bc5a78b04ed08dee7924516c5e90

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c951bc5a78b04ed08dee7924516c5e90

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-025-93029-x

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