Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms
Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Activin receptor-like kinase 1 (ALK1)-mediated endothelial cell signalling in response to bone morphogenetic protein 9 (BMP9) and BMP10 is of significant importance in cardiovascular disease and cancer. However, detailed molecular mechanisms of ALK1-mediated signalling remain unclear. Here, we report crystal structures of the BMP10:ALK1 complex at...
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Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms
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TN_cdi_doaj_primary_oai_doaj_org_article_c95928c8f6c04cf69fb1889c1608aeab
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c95928c8f6c04cf69fb1889c1608aeab
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15425-3
