Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by l...
Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice
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Author / Creator
Zhao, Weixing , Xu, Zhipeng , Cao, Jiangbei , Fu, Qiang , Wu, Yishuang , Zhang, Xiaoying , Long, Yue , Zhang, Xuan , Yang, Yitian , Li, Yunfeng and Mi, Weidong
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
It is widely accepted that mitochondria have a direct impact on neuronal function and survival. Oxidative stress caused by mitochondrial abnormalities play an important role in the pathophysiology of lipopolysaccharide (LPS)-induced memory impairment. Elamipretide (SS-31) is a novel mitochondrion-targeted antioxidant. However, the impact of elamipr...
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Full title
Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_c95be8e71c1c4d2a97407cb17eab032e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c95be8e71c1c4d2a97407cb17eab032e
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-019-1627-9
