Induction of immunosuppressive functions and NF-κB by FLIP in monocytes
Induction of immunosuppressive functions and NF-κB by FLIP in monocytes
About this item
Full title
Author / Creator
Fiore, Alessandra , Ugel, Stefano , De Sanctis, Francesco , Sandri, Sara , Fracasso, Giulio , Trovato, Rosalinda , Sartoris, Silvia , Solito, Samantha , Mandruzzato, Susanna , Vascotto, Fulvia , Hippen, Keli L. , Mondanelli, Giada , Grohmann, Ursula , Piro, Geny , Carbone, Carmine , Melisi, Davide , Lawlor, Rita T. , Scarpa, Aldo , Lamolinara, Alessia , Iezzi, Manuela , Fassan, Matteo , Bicciato, Silvio , Blazar, Bruce R. , Sahin, Ugur , Murray, Peter J. and Bronte, Vincenzo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Immunosuppression is a hallmark of tumor progression, and treatments that inhibit or deplete monocytic myeloid-derived suppressive cells could promote anti-tumor immunity. c-FLIP is a central regulator of caspase-8-mediated apoptosis and necroptosis. Here we show that low-dose cytotoxic chemotherapy agents cause apoptosis linked to c-FLIP down-regu...
Alternative Titles
Full title
Induction of immunosuppressive functions and NF-κB by FLIP in monocytes
Authors, Artists and Contributors
Author / Creator
Ugel, Stefano
De Sanctis, Francesco
Sandri, Sara
Fracasso, Giulio
Trovato, Rosalinda
Sartoris, Silvia
Solito, Samantha
Mandruzzato, Susanna
Vascotto, Fulvia
Hippen, Keli L.
Mondanelli, Giada
Grohmann, Ursula
Piro, Geny
Carbone, Carmine
Melisi, Davide
Lawlor, Rita T.
Scarpa, Aldo
Lamolinara, Alessia
Iezzi, Manuela
Fassan, Matteo
Bicciato, Silvio
Blazar, Bruce R.
Sahin, Ugur
Murray, Peter J.
Bronte, Vincenzo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c988a8bcde8c4a15aa07366b491c041d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c988a8bcde8c4a15aa07366b491c041d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07654-4
