Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer
Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer
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Author / Creator
Baca, Sylvan C. , Takeda, David Y. , Seo, Ji-Heui , Hwang, Justin , Ku, Sheng Yu , Arafeh, Rand , Arnoff, Taylor , Agarwal, Supreet , Bell, Connor , O’Connor, Edward , Qiu, Xintao , Alaiwi, Sarah Abou , Corona, Rosario I. , Fonseca, Marcos A. S. , Giambartolomei, Claudia , Cejas, Paloma , Lim, Klothilda , He, Monica , Sheahan, Anjali , Nassar, Amin , Berchuck, Jacob E. , Brown, Lisha , Nguyen, Holly M. , Coleman, Ilsa M. , Kaipainen, Arja , De Sarkar, Navonil , Nelson, Peter S. , Morrissey, Colm , Korthauer, Keegan , Pomerantz, Mark M. , Ellis, Leigh , Pasaniuc, Bogdan , Lawrenson, Kate , Kelly, Kathleen , Zoubeidi, Amina , Hahn, William C. , Beltran, Himisha , Long, Henry W. , Brown, Myles , Corey, Eva and Freedman, Matthew L.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Lineage plasticity, the ability of a cell to alter its identity, is an increasingly common mechanism of adaptive resistance to targeted therapy in cancer. An archetypal example is the development of neuroendocrine prostate cancer (NEPC) after treatment of prostate adenocarcinoma (PRAD) with inhibitors of androgen signaling. NEPC is an aggressive va...
Alternative Titles
Full title
Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer
Authors, Artists and Contributors
Author / Creator
Takeda, David Y.
Seo, Ji-Heui
Hwang, Justin
Ku, Sheng Yu
Arafeh, Rand
Arnoff, Taylor
Agarwal, Supreet
Bell, Connor
O’Connor, Edward
Qiu, Xintao
Alaiwi, Sarah Abou
Corona, Rosario I.
Fonseca, Marcos A. S.
Giambartolomei, Claudia
Cejas, Paloma
Lim, Klothilda
He, Monica
Sheahan, Anjali
Nassar, Amin
Berchuck, Jacob E.
Brown, Lisha
Nguyen, Holly M.
Coleman, Ilsa M.
Kaipainen, Arja
De Sarkar, Navonil
Nelson, Peter S.
Morrissey, Colm
Korthauer, Keegan
Pomerantz, Mark M.
Ellis, Leigh
Pasaniuc, Bogdan
Lawrenson, Kate
Kelly, Kathleen
Zoubeidi, Amina
Hahn, William C.
Beltran, Himisha
Long, Henry W.
Brown, Myles
Corey, Eva
Freedman, Matthew L.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c9b61c7dcf794ef5947cc08ad8806fa3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c9b61c7dcf794ef5947cc08ad8806fa3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22139-7