Structural basis for tRNA-dependent cysteine biosynthesis
Structural basis for tRNA-dependent cysteine biosynthesis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Cysteine can be synthesized by tRNA-dependent mechanism using a two-step indirect pathway, where
O
-phosphoseryl-tRNA synthetase (SepRS) catalyzes the ligation of a mismatching
O
-phosphoserine (Sep) to tRNA
Cys
followed by the conversion of tRNA-bounded Sep into cysteine by Sep-tRNA:Cys-tRNA synthase (SepCysS). In ancestral metha...
Alternative Titles
Full title
Structural basis for tRNA-dependent cysteine biosynthesis
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TN_cdi_doaj_primary_oai_doaj_org_article_c9bee99cff4f4579934ca24282231251
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c9bee99cff4f4579934ca24282231251
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01543-y