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Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in me...

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in me...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c9d92eaf516942b2a0096a914c190758

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells

About this item

Full title

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells

Publisher

England: BioMed Central Ltd

Journal title

BMC cancer, 2012-03, Vol.12 (1), p.80-80, Article 80

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Medulloblastoma is the most common malignant brain tumor in children and remains a therapeutic challenge due to its significant therapy-related morbidity. Polo-like kinase 1 (PLK1) is highly expressed in many cancers and regulates critical steps in mitotic progression. Recent studies suggest that targeting PLK1 with small molecule inhibitors is a p...

Alternative Titles

Full title

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c9d92eaf516942b2a0096a914c190758

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c9d92eaf516942b2a0096a914c190758

Other Identifiers

ISSN

1471-2407

E-ISSN

1471-2407

DOI

10.1186/1471-2407-12-80

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