Coupled pre‐mRNA and mRNA dynamics unveil operational strategies underlying transcriptional response...
Coupled pre‐mRNA and mRNA dynamics unveil operational strategies underlying transcriptional responses to stimuli
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Transcriptional responses to extracellular stimuli involve tuning the rates of transcript production and degradation. Here, we show that the time‐dependent profiles of these rates can be inferred from simultaneous measurements of precursor mRNA (pre‐mRNA) and mature mRNA profiles. Transcriptome‐wide measurements demonstrate that genes with similar...
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Coupled pre‐mRNA and mRNA dynamics unveil operational strategies underlying transcriptional responses to stimuli
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TN_cdi_doaj_primary_oai_doaj_org_article_c9f4f89d361746d3a5307cf5b5df600b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c9f4f89d361746d3a5307cf5b5df600b
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ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.1038/msb.2011.62
