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Analysis of NS2-dependent effects on influenza PB1 segment extends replication requirements beyond t...

Analysis of NS2-dependent effects on influenza PB1 segment extends replication requirements beyond t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca10196771194cd2a4e0d232f4c0297c

Analysis of NS2-dependent effects on influenza PB1 segment extends replication requirements beyond the canonical promoter

About this item

Full title

Analysis of NS2-dependent effects on influenza PB1 segment extends replication requirements beyond the canonical promoter

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2025-02, Vol.16 (1), p.1875-15, Article 1875

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Influenza A virus encodes conserved promoter sequences. Using minimal replication assays—transfections with viral polymerase, nucleoprotein, and a genomic template—these sequences were identified as 13nt at the 5’ end of the genomic RNA (U13) and 12nt at the 3’ end (U12). Other than the fourth 3’ nucleotide, the U12 and U13 sequences are identical...

Alternative Titles

Full title

Analysis of NS2-dependent effects on influenza PB1 segment extends replication requirements beyond the canonical promoter

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ca10196771194cd2a4e0d232f4c0297c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca10196771194cd2a4e0d232f4c0297c

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-025-57092-2

How to access this item