Recently activated CD4 T cells in tuberculosis express OX40 as a target for host-directed immunother...
Recently activated CD4 T cells in tuberculosis express OX40 as a target for host-directed immunotherapy
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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After Mycobacterium tuberculosis (Mtb) infection, many effector T cells traffic to the lungs, but few become activated. Here we use an antigen receptor reporter mouse (Nur77-GFP) to identify recently activated CD4 T cells in the lungs. These Nur77-GFP
HI
cells contain expanded TCR clonotypes, have elevated expression of co-stimulatory genes s...
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Full title
Recently activated CD4 T cells in tuberculosis express OX40 as a target for host-directed immunotherapy
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TN_cdi_doaj_primary_oai_doaj_org_article_ca259876e3be47d9b437b62b4a3c7cd7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca259876e3be47d9b437b62b4a3c7cd7
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-44152-8
