Novel extracellular and nuclear caspase-1 and inflammasomes propagate inflammation and regulate gene...
Novel extracellular and nuclear caspase-1 and inflammasomes propagate inflammation and regulate gene expression: a comprehensive database mining study
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England: BioMed Central Ltd
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English
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Publisher
England: BioMed Central Ltd
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Caspase-1 is present in the cytosol as an inactive zymogen and requires the protein complexes named "inflammasomes" for proteolytic activation. However, it remains unclear whether the proteolytic activity of caspase-1 is confined only to the cytosol where inflammasomes are assembled to convert inactive pro-caspase-1 to active caspase-1.
We condu...
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Novel extracellular and nuclear caspase-1 and inflammasomes propagate inflammation and regulate gene expression: a comprehensive database mining study
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TN_cdi_doaj_primary_oai_doaj_org_article_ca2c6fc1d40345bb8dc4eba79b750c8e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca2c6fc1d40345bb8dc4eba79b750c8e
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ISSN
1756-8722
E-ISSN
1756-8722
DOI
10.1186/s13045-016-0351-5
