Activation of mitochondrial TUFM ameliorates metabolic dysregulation through coordinating autophagy...
Activation of mitochondrial TUFM ameliorates metabolic dysregulation through coordinating autophagy induction
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Disorders of autophagy, a key regulator of cellular homeostasis, cause a number of human diseases. Due to the role of autophagy in metabolic dysregulation, there is a need to identify autophagy regulators as therapeutic targets. To address this need, we conducted an autophagy phenotype-based screen and identified the natural compound kaempferide (K...
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Activation of mitochondrial TUFM ameliorates metabolic dysregulation through coordinating autophagy induction
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TN_cdi_doaj_primary_oai_doaj_org_article_ca2eeb930c9945b6b07d31949a91e055
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca2eeb930c9945b6b07d31949a91e055
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2399-3642
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2399-3642
DOI
10.1038/s42003-020-01566-0