Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen
Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen
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Author / Creator
Miguel-Blanco, Celia , Molina, Irene , Bardera, Ana I. , Díaz, Beatriz , de las Heras, Laura , Lozano, Sonia , González, Carolina , Rodrigues, Janneth , Delves, Michael J. , Ruecker, Andrea , Colmenarejo, Gonzalo , Viera, Sara , Martínez-Martínez, María S. , Fernández, Esther , Baum, Jake , Sinden, Robert E. and Herreros, Esperanza
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Plasmodium falciparum
stage V gametocytes are responsible for parasite transmission, and drugs targeting this stage are needed to support malaria elimination. We here screen the Tres Cantos Antimalarial Set (TCAMS) using the previously developed
P. falciparum
female gametocyte activation assay (
Pf
FGAA), which assesses stage V femal...
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Full title
Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen
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TN_cdi_doaj_primary_oai_doaj_org_article_ca4505d3d02c492988049e0313f6978a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca4505d3d02c492988049e0313f6978a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15160
