Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through...
Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through regulating the HIF1-α/PDK4 axis in non-small cell lung cancer
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England: BioMed Central
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English
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England: BioMed Central
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Ginsenoside Rh2 (G-Rh2), a steroidal compound extracted from roots of ginseng, has been extensively studied in tumor therapy. However, its specific regulatory mechanism in non-small cell lung cancer (NSCLC) is not well understood. Pyruvate dehydrogenase kinase 4 (PDK4), a central regulator of cellular energy metabolism, is highly expressed in vario...
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Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through regulating the HIF1-α/PDK4 axis in non-small cell lung cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_ca55076101014d8c8eeb2be3eaa53bae
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca55076101014d8c8eeb2be3eaa53bae
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ISSN
1528-3658,1076-1551
E-ISSN
1528-3658
DOI
10.1186/s10020-024-00813-y