Anticancer Effects of Abietane Diterpene 7α-Acetoxy-6β-hydroxyroyleanone from Plectranthus grandiden...
Anticancer Effects of Abietane Diterpene 7α-Acetoxy-6β-hydroxyroyleanone from Plectranthus grandidentatus and Its Semi-Synthetic Analogs: An In Silico Computational Approach
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Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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Contents
The abietane diterpenoid 7α-acetoxy-6β-hydroxyroyleanone (Roy) isolated from
demonstrates cytotoxicity across numerous cancer cell lines. To potentiate anticancer attributes, a series of semi-synthetic Roy derivatives were generated and examined computationally. ADMET predictions were used to evaluate drug-likeness and toxicity risks. The antine...
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Full title
Anticancer Effects of Abietane Diterpene 7α-Acetoxy-6β-hydroxyroyleanone from Plectranthus grandidentatus and Its Semi-Synthetic Analogs: An In Silico Computational Approach
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TN_cdi_doaj_primary_oai_doaj_org_article_ca6cc14bfa5649288219b0f8d5e9fb4e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca6cc14bfa5649288219b0f8d5e9fb4e
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules29081807
