1338 Crystallography-guided characterization of novel cytosolic DNase 3’ repair exonuclease 1 (TREX1...
1338 Crystallography-guided characterization of novel cytosolic DNase 3’ repair exonuclease 1 (TREX1) inhibitors
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London: BMJ Publishing Group Ltd
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English
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London: BMJ Publishing Group Ltd
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BackgroundThe stimulator of interferon genes (STING) protein is an innate immune sensor critical for the development of immunity. Tumor cells frequently inactivate the STING pathway to avoid immune recognition, emphasizing its importance in generating tumor-specific immunity. Broad tumor-specific activation of STING in advanced cancers may be requi...
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1338 Crystallography-guided characterization of novel cytosolic DNase 3’ repair exonuclease 1 (TREX1) inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_ca78ca8b3c1f47f78fdbc08e6d55ce0d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca78ca8b3c1f47f78fdbc08e6d55ce0d
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E-ISSN
2051-1426
DOI
10.1136/jitc-2023-SITC2023.1338
