Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via pair...
Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS
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Author / Creator
Rose Brannon, A. , Jayakumaran, Gowtham , Diosdado, Monica , Patel, Juber , Razumova, Anna , Hu, Yu , Meng, Fanli , Haque, Mohammad , Sadowska, Justyna , Murphy, Brian J. , Baldi, Tessara , Johnson, Ian , Ptashkin, Ryan , Hasan, Maysun , Srinivasan, Preethi , Rema, Anoop Balakrishnan , Rijo, Ivelise , Agarunov, Aaron , Won, Helen , Perera, Dilmi , Brown, David N. , Samoila, Aliaksandra , Jing, Xiaohong , Gedvilaite, Erika , Yang, Julie L. , Stephens, Dennis P. , Dix, Jenna-Marie , DeGroat, Nicole , Nafa, Khedoudja , Syed, Aijazuddin , Li, Alan , Lebow, Emily S. , Bowman, Anita S. , Ferguson, Donna C. , Liu, Ying , Mata, Douglas A. , Sharma, Rohit , Yang, Soo-Ryum , Bale, Tejus , Benhamida, Jamal K. , Chang, Jason C. , Dogan, Snjezana , Hameed, Meera R. , Hechtman, Jaclyn F. , Moung, Christine , Ross, Dara S. , Vakiani, Efsevia , Vanderbilt, Chad M. , Yao, JinJuan , Razavi, Pedram , Smyth, Lillian M. , Chandarlapaty, Sarat , Iyer, Gopa , Abida, Wassim , Harding, James J. , Krantz, Benjamin , O’Reilly, Eileen , Yu, Helena A. , Li, Bob T. , Rudin, Charles M. , Diaz, Luis , Solit, David B. , Arcila, Maria E. , Ladanyi, Marc , Loomis, Brian , Tsui, Dana , Berger, Michael F. , Zehir, Ahmet and Benayed, Ryma
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Circulating cell-free DNA from blood plasma of cancer patients can be used to non-invasively interrogate somatic tumor alterations. Here we develop MSK-ACCESS (Memorial Sloan Kettering - Analysis of Circulating cfDNA to Examine Somatic Status), an NGS assay for detection of very low frequency somatic alterations in 129 genes. Analytical validation...
Alternative Titles
Full title
Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS
Authors, Artists and Contributors
Author / Creator
Jayakumaran, Gowtham
Diosdado, Monica
Patel, Juber
Razumova, Anna
Hu, Yu
Meng, Fanli
Haque, Mohammad
Sadowska, Justyna
Murphy, Brian J.
Baldi, Tessara
Johnson, Ian
Ptashkin, Ryan
Hasan, Maysun
Srinivasan, Preethi
Rema, Anoop Balakrishnan
Rijo, Ivelise
Agarunov, Aaron
Won, Helen
Perera, Dilmi
Brown, David N.
Samoila, Aliaksandra
Jing, Xiaohong
Gedvilaite, Erika
Yang, Julie L.
Stephens, Dennis P.
Dix, Jenna-Marie
DeGroat, Nicole
Nafa, Khedoudja
Syed, Aijazuddin
Li, Alan
Lebow, Emily S.
Bowman, Anita S.
Ferguson, Donna C.
Liu, Ying
Mata, Douglas A.
Sharma, Rohit
Yang, Soo-Ryum
Bale, Tejus
Benhamida, Jamal K.
Chang, Jason C.
Dogan, Snjezana
Hameed, Meera R.
Hechtman, Jaclyn F.
Moung, Christine
Ross, Dara S.
Vakiani, Efsevia
Vanderbilt, Chad M.
Yao, JinJuan
Razavi, Pedram
Smyth, Lillian M.
Chandarlapaty, Sarat
Iyer, Gopa
Abida, Wassim
Harding, James J.
Krantz, Benjamin
O’Reilly, Eileen
Yu, Helena A.
Li, Bob T.
Rudin, Charles M.
Diaz, Luis
Solit, David B.
Arcila, Maria E.
Ladanyi, Marc
Loomis, Brian
Tsui, Dana
Berger, Michael F.
Zehir, Ahmet
Benayed, Ryma
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ca7c61a9651341a5819f1ee6a4c47bfa
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca7c61a9651341a5819f1ee6a4c47bfa
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24109-5
