Enhanced Ca2+-channeling complex formation at the ER-mitochondria interface underlies the pathogenes...
Enhanced Ca2+-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease
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Author / Creator
Thoudam, Themis , Chanda, Dipanjan , Lee, Jung Yi , Jung, Min-Kyo , Sinam, Ibotombi Singh , Kim, Byung-Gyu , Park, Bo-Yoon , Kwon, Woong Hee , Kim, Hyo-Jeong , Kim, Myeongjin , Lim, Chae Won , Lee, Hoyul , Huh, Yang Hoon , Miller, Caroline A. , Saxena, Romil , Skill, Nicholas J. , Huda, Nazmul , Kusumanchi, Praveen , Ma, Jing , Yang, Zhihong , Kim, Min-Ji , Mun, Ji Young , Harris, Robert A. , Jeon, Jae-Han , Liangpunsakul, Suthat and Lee, In-Kyu
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Ca
2+
overload-induced mitochondrial dysfunction is considered as a major contributing factor in the pathogenesis of alcohol-associated liver disease (ALD). However, the initiating factors that drive mitochondrial Ca
2+
accumulation in ALD remain elusive. Here, we demonstrate that an aberrant increase in hepatic GRP75-mediated mitochond...
Alternative Titles
Full title
Enhanced Ca2+-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease
Authors, Artists and Contributors
Author / Creator
Chanda, Dipanjan
Lee, Jung Yi
Jung, Min-Kyo
Sinam, Ibotombi Singh
Kim, Byung-Gyu
Park, Bo-Yoon
Kwon, Woong Hee
Kim, Hyo-Jeong
Kim, Myeongjin
Lim, Chae Won
Lee, Hoyul
Huh, Yang Hoon
Miller, Caroline A.
Saxena, Romil
Skill, Nicholas J.
Huda, Nazmul
Kusumanchi, Praveen
Ma, Jing
Yang, Zhihong
Kim, Min-Ji
Mun, Ji Young
Harris, Robert A.
Jeon, Jae-Han
Liangpunsakul, Suthat
Lee, In-Kyu
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ca818281f2e2456cb8d5bb15f28a64a9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca818281f2e2456cb8d5bb15f28a64a9
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-37214-4
