Signal sequence-triage is activated by translocon obstruction sensed by an ER stress sensor IRE1α
Signal sequence-triage is activated by translocon obstruction sensed by an ER stress sensor IRE1α
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Japan: Japan Society for Cell Biology
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Language
English
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Japan: Japan Society for Cell Biology
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Secretory pathway proteins are cotranslationally translocated into the endoplasmic reticulum (ER) of metazoan cells through the protein channel, translocon. Given that there are far fewer translocons than ribosomes in a cell, it is essential that secretory protein-translating ribosomes only occupy translocons transiently. Therefore, if translocons...
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Full title
Signal sequence-triage is activated by translocon obstruction sensed by an ER stress sensor IRE1α
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TN_cdi_doaj_primary_oai_doaj_org_article_cad2245e20b043869e0ac315ead82998
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cad2245e20b043869e0ac315ead82998
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ISSN
0386-7196,1347-3700
E-ISSN
1347-3700
DOI
10.1247/csf.23072
