PKM2 Knockdown Induces Autophagic Cell Death via AKT/mTOR Pathway in Human Prostate Cancer Cells
PKM2 Knockdown Induces Autophagic Cell Death via AKT/mTOR Pathway in Human Prostate Cancer Cells
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Germany: Cell Physiol Biochem Press GmbH & Co KG
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English
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Germany: Cell Physiol Biochem Press GmbH & Co KG
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Pyruvate kinase M2 (PKM2) is essential for aerobic glycolysis. Although high PKM2 expression is observed in various cancer tissues, its functional role in cancer metabolism is unclear. Here, we investigated the role of PKM2 in regulating autophagy and its associated pathways in prostate cancer cells.
Immunohistochemistry was performed to compare...
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PKM2 Knockdown Induces Autophagic Cell Death via AKT/mTOR Pathway in Human Prostate Cancer Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_cb136f60ad954351a8ad06106855089d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cb136f60ad954351a8ad06106855089d
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ISSN
1015-8987
E-ISSN
1421-9778
DOI
10.33594/000000107
