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Non-destructive crystallinity assessment of indomethacin in tablets made from smartFilms® using tera...

Non-destructive crystallinity assessment of indomethacin in tablets made from smartFilms® using tera...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cb2d9ae5c8764e22a1012f6bc66baaee

Non-destructive crystallinity assessment of indomethacin in tablets made from smartFilms® using terahertz time-domain spectroscopy

About this item

Full title

Non-destructive crystallinity assessment of indomethacin in tablets made from smartFilms® using terahertz time-domain spectroscopy

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-04, Vol.12 (1), p.6099-6099, Article 6099

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

We use terahertz (THz) time-domain spectroscopy (TDS) to assess the crystalline state of indomethacin (IM) when loaded in smartFilms®. We found that smartFilms favour the amorphous IM (A-IM) for low loading concentrations. For higher concentrations, IM recrystallizes in its
α
- crystalline form and the amount of A-IM in the smartFilms reduces...

Alternative Titles

Full title

Non-destructive crystallinity assessment of indomethacin in tablets made from smartFilms® using terahertz time-domain spectroscopy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cb2d9ae5c8764e22a1012f6bc66baaee

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cb2d9ae5c8764e22a1012f6bc66baaee

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-10041-1

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