Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway
Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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The inflammation and oxidative stress (OS) have been considered crucial components of the pathogenesis of depression. Edaravone (EDA), a free radical scavenger, processes strong biological activities including antioxidant, anti-inflammatory and neuroprotective properties. However, its role and potential molecular mechanisms in depression remain unc...
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Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_cb39fd5afd034f49bde8901f45eb9ec3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cb39fd5afd034f49bde8901f45eb9ec3
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-022-02400-6
