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363 Vactosertib and durvalumab as second or later line treatment for PD-L1 positive non-small cell l...

363 Vactosertib and durvalumab as second or later line treatment for PD-L1 positive non-small cell l...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cb60369c59fb483d857b8b1164e37f4b

363 Vactosertib and durvalumab as second or later line treatment for PD-L1 positive non-small cell lung cancer: interim result

About this item

Full title

363 Vactosertib and durvalumab as second or later line treatment for PD-L1 positive non-small cell lung cancer: interim result

Publisher

London: BMJ Publishing Group LTD

Journal title

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A388-A388

Language

English

Formats

Publication information

Publisher

London: BMJ Publishing Group LTD

More information

Scope and Contents

Contents

BackgroundTargeting transforming growth factor-β (TGF-β) is reported to augment the efficacy of immune checkpoint inhibitors (ICIs) through either enhanced anti-tumor immunity or the correction of tumor microenvironment (TME). Therefore, the combination of vactosertib, a highly selective TGF-β RI kinase inhibitor, and durvalumab is anticipated to i...

Alternative Titles

Full title

363 Vactosertib and durvalumab as second or later line treatment for PD-L1 positive non-small cell lung cancer: interim result

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cb60369c59fb483d857b8b1164e37f4b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cb60369c59fb483d857b8b1164e37f4b

Other Identifiers

E-ISSN

2051-1426

DOI

10.1136/jitc-2020-SITC2020.0363

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