Enantioselective synthesis of cis-hydrobenzofurans bearing all-carbon quaternary stereocenters and a...
Enantioselective synthesis of cis-hydrobenzofurans bearing all-carbon quaternary stereocenters and application to total synthesis of (‒)-morphine
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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(‒)-Morphine, which is selected as an essential medicine by World Health Organization, is widely applied in the treatment of the pain-related diseases. Due to its synthetically challenging molecular architecture and important clinical role, extensive synthetic studies of morphine-type alkaloids have been conducted. However, catalytic asymmetric tot...
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Enantioselective synthesis of cis-hydrobenzofurans bearing all-carbon quaternary stereocenters and application to total synthesis of (‒)-morphine
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TN_cdi_doaj_primary_oai_doaj_org_article_cb927e17afa2486397458cec4dc97f09
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cb927e17afa2486397458cec4dc97f09
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10398-4
