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A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regu...

A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cba2a41fe96a4a9f9401576c24fe4ce7

A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes

About this item

Full title

A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-03, Vol.11 (1), p.6518-6518, Article 6518

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The transcription factor vitamin D receptor (VDR) is the high affinity nuclear target of the biologically active form of vitamin D
3
(1,25(OH)
2
D
3
). In order to identify pure genomic transcriptional effects of 1,25(OH)
2
D
3
, we used VDR cistrome, transcriptome and open chromatin data, obtained from the human monoc...

Alternative Titles

Full title

A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cba2a41fe96a4a9f9401576c24fe4ce7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cba2a41fe96a4a9f9401576c24fe4ce7

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-86032-5

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