Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early tri...
Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early triple negative breast cancers
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Author / Creator
Derouane, Françoise , Desgres, Manon , Moroni, Camilla , Ambroise, Jérôme , Berlière, Martine , Van Bockstal, Mieke R. , Galant, Christine , van Marcke, Cédric , Vara-Messler, Marianela , Hutten, Stefan J. , Jonkers, Jos , Mourao, Larissa , Scheele, Colinda L. G. J. , Duhoux, Francois P. and Corbet, Cyril
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Neoadjuvant chemotherapy (NAC) is the standard of care for patients with early-stage triple negative breast cancers (TNBC). However, more than half of TNBC patients do not achieve a pathological complete response (pCR) after NAC, and residual cancer burden (RCB) is associated with dismal long-term prognosis. Understanding the mechanisms underlying...
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Full title
Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early triple negative breast cancers
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cbcb7ddcc69b4cbbb96f42be1600415c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cbcb7ddcc69b4cbbb96f42be1600415c
Other Identifiers
ISSN
1465-542X,1465-5411
E-ISSN
1465-542X
DOI
10.1186/s13058-024-01788-8
