Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W
Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W
About this item
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Author / Creator
Davies, Christopher W. , Vidal, Simon E. , Phu, Lilian , Sudhamsu, Jawahar , Hinkle, Trent B. , Chan Rosenberg, Scott , Schumacher, Frances-Rose , Zeng, Yi Jimmy , Schwerdtfeger, Carsten , Peterson, Andrew S. , Lill, Jennie R. , Rose, Christopher M. , Shaw, Andrey S. , Wertz, Ingrid E. , Kirkpatrick, Donald S. and Koerber, James T.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The ubiquitin conjugating enzyme UBE2W catalyzes non-canonical ubiquitination on the N-termini of proteins, although its substrate repertoire remains unclear. To identify endogenous N-terminally-ubiquitinated substrates, we discover four monoclonal antibodies that selectively recognize tryptic peptides with an N-terminal diglycine remnant, correspo...
Alternative Titles
Full title
Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W
Authors, Artists and Contributors
Author / Creator
Vidal, Simon E.
Phu, Lilian
Sudhamsu, Jawahar
Hinkle, Trent B.
Chan Rosenberg, Scott
Schumacher, Frances-Rose
Zeng, Yi Jimmy
Schwerdtfeger, Carsten
Peterson, Andrew S.
Lill, Jennie R.
Rose, Christopher M.
Shaw, Andrey S.
Wertz, Ingrid E.
Kirkpatrick, Donald S.
Koerber, James T.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cbfb2674260f4b51a1c495c83e07dcb5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cbfb2674260f4b51a1c495c83e07dcb5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24669-6
