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EF-hand motifs of diacylglycerol kinase α interact intra-molecularly with its C1 domains

EF-hand motifs of diacylglycerol kinase α interact intra-molecularly with its C1 domains

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc165640042544a88fa5f6f1c1aef1cc

EF-hand motifs of diacylglycerol kinase α interact intra-molecularly with its C1 domains

About this item

Full title

EF-hand motifs of diacylglycerol kinase α interact intra-molecularly with its C1 domains

Publisher

England: Elsevier B.V

Journal title

FEBS open bio, 2014-01, Vol.4 (1), p.387-392

Language

English

Formats

Publication information

Publisher

England: Elsevier B.V

More information

Scope and Contents

Contents

[Display omitted]
•We revealed the intra-molecular interaction of DGKα.•The EF-hand motifs of DGKα directly binds to its C1 domains.•The intra-molecular interaction was negatively regulated by Ca2+.•The intra-molecular interaction is important for the activation mechanism of DGKα.
Diacylglycerol kinase (DGK) α, which is activated by Ca2+, con...

Alternative Titles

Full title

EF-hand motifs of diacylglycerol kinase α interact intra-molecularly with its C1 domains

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cc165640042544a88fa5f6f1c1aef1cc

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc165640042544a88fa5f6f1c1aef1cc

Other Identifiers

ISSN

2211-5463

E-ISSN

2211-5463

DOI

10.1016/j.fob.2014.04.003

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