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Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis

Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc3b96a86db74fb2bb59bfc9050c1baa

Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis

About this item

Full title

Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-09, Vol.11 (1), p.4524-18, Article 4524

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Traumatic brain injury (TBI) is a leading global cause of death and disability. Here we demonstrate in an experimental mouse model of TBI that mild forms of brain trauma cause severe deficits in meningeal lymphatic drainage that begin within hours and last out to at least one month post-injury. To investigate a mechanism underlying impaired lymphat...

Alternative Titles

Full title

Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cc3b96a86db74fb2bb59bfc9050c1baa

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc3b96a86db74fb2bb59bfc9050c1baa

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-18113-4

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