Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemicha...
Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders
About this item
Full title
Author / Creator
Xu, Liang , Carrer, Andrea , Zonta, Francesco , Qu, Zhihu , Ma, Peixiang , Li, Sheng , Ceriani, Federico , Buratto, Damiano , Crispino, Giulia , Zorzi, Veronica , Ziraldo, Gaia , Bruno, Francesca , Nardin, Chiara , Peres, Chiara , Mazzarda, Flavia , Salvatore, Anna M. , Raspa, Marcello , Scavizzi, Ferdinando , Chu, Youjun , Xie, Sichun , Yang, Xuemei , Liao, Jun , Liu, Xiao , Wang, Wei , Wang, Shanshan , Yang, Guang , Lerner, Richard A. and Mammano, Fabio
Publisher
Switzerland: Frontiers Research Foundation
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: Frontiers Research Foundation
Subjects
More information
Scope and Contents
Contents
Mutations leading to changes in properties, regulation, or expression of connexin-made channels have been implicated in 28 distinct human hereditary diseases. Eight of these result from variants of connexin 26 (Cx26), a protein critically involved in cell-cell signaling in the inner ear and skin. Lack of non-toxic drugs with defined mechanisms of a...
Alternative Titles
Full title
Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders
Authors, Artists and Contributors
Author / Creator
Carrer, Andrea
Zonta, Francesco
Qu, Zhihu
Ma, Peixiang
Li, Sheng
Ceriani, Federico
Buratto, Damiano
Crispino, Giulia
Zorzi, Veronica
Ziraldo, Gaia
Bruno, Francesca
Nardin, Chiara
Peres, Chiara
Mazzarda, Flavia
Salvatore, Anna M.
Raspa, Marcello
Scavizzi, Ferdinando
Chu, Youjun
Xie, Sichun
Yang, Xuemei
Liao, Jun
Liu, Xiao
Wang, Wei
Wang, Shanshan
Yang, Guang
Lerner, Richard A.
Mammano, Fabio
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cc3dd804c27e4ae68e8efa44292bdd38
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc3dd804c27e4ae68e8efa44292bdd38
Other Identifiers
ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2017.00298
