Lomitapide modifies high-density lipoprotein function in homozygous familial hypercholesterolaemia
Lomitapide modifies high-density lipoprotein function in homozygous familial hypercholesterolaemia
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Lomitapide reduces plasma low-density lipoprotein cholesterol (LDL-C) and is approved for the treatment of homozygous familial hypercholesterolemia (HoFH). This study aims to determine the effect of lomitapide on HDL and cholesterol efflux in a cohort of patients with HoFH.
Analysis included plasma samples from 17 HoFH patients enrolled in the l...
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Lomitapide modifies high-density lipoprotein function in homozygous familial hypercholesterolaemia
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TN_cdi_doaj_primary_oai_doaj_org_article_cc467f83de66482ea1e832f4391954d7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc467f83de66482ea1e832f4391954d7
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ISSN
2047-783X,0949-2321
E-ISSN
2047-783X
DOI
10.1186/s40001-025-02439-0