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Lomitapide modifies high-density lipoprotein function in homozygous familial hypercholesterolaemia

Lomitapide modifies high-density lipoprotein function in homozygous familial hypercholesterolaemia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc467f83de66482ea1e832f4391954d7

Lomitapide modifies high-density lipoprotein function in homozygous familial hypercholesterolaemia

About this item

Full title

Lomitapide modifies high-density lipoprotein function in homozygous familial hypercholesterolaemia

Publisher

England: BioMed Central Ltd

Journal title

European journal of medical research, 2025-04, Vol.30 (1), p.266-9, Article 266

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Lomitapide reduces plasma low-density lipoprotein cholesterol (LDL-C) and is approved for the treatment of homozygous familial hypercholesterolemia (HoFH). This study aims to determine the effect of lomitapide on HDL and cholesterol efflux in a cohort of patients with HoFH.
Analysis included plasma samples from 17 HoFH patients enrolled in the l...

Alternative Titles

Full title

Lomitapide modifies high-density lipoprotein function in homozygous familial hypercholesterolaemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cc467f83de66482ea1e832f4391954d7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc467f83de66482ea1e832f4391954d7

Other Identifiers

ISSN

2047-783X,0949-2321

E-ISSN

2047-783X

DOI

10.1186/s40001-025-02439-0

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