rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type...
rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences
About this item
Full title
Author / Creator
Sellier, Chantal , Cerro-Herreros, Estefanía , Blatter, Markus , Freyermuth, Fernande , Gaucherot, Angeline , Ruffenach, Frank , Sarkar, Partha , Puymirat, Jack , Udd, Bjarne , Day, John W. , Meola, Giovanni , Bassez, Guillaume , Fujimura, Harutoshi , Takahashi, Masanori P. , Schoser, Benedikt , Furling, Denis , Artero, Ruben , Allain, Frédéric H. T. , Llamusi, Beatriz and Charlet-Berguerand, Nicolas
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Myotonic dystrophy type 1 and type 2 (DM1, DM2) are caused by expansions of CTG and CCTG repeats, respectively. RNAs containing expanded CUG or CCUG repeats interfere with the metabolism of other RNAs through titration of the Muscleblind-like (MBNL) RNA binding proteins. DM2 follows a more favorable clinical course than DM1, suggesting that specifi...
Alternative Titles
Full title
rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences
Authors, Artists and Contributors
Author / Creator
Cerro-Herreros, Estefanía
Blatter, Markus
Freyermuth, Fernande
Gaucherot, Angeline
Ruffenach, Frank
Sarkar, Partha
Puymirat, Jack
Udd, Bjarne
Day, John W.
Meola, Giovanni
Bassez, Guillaume
Fujimura, Harutoshi
Takahashi, Masanori P.
Schoser, Benedikt
Furling, Denis
Artero, Ruben
Allain, Frédéric H. T.
Llamusi, Beatriz
Charlet-Berguerand, Nicolas
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cc4a1e87ad4646d6a2914e7d2348f083
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc4a1e87ad4646d6a2914e7d2348f083
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04370-x
