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Brain clusterin protein isoforms and mitochondrial localization

Brain clusterin protein isoforms and mitochondrial localization

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc6acdd30eb144ba92c144ec53ff6c43

Brain clusterin protein isoforms and mitochondrial localization

About this item

Full title

Brain clusterin protein isoforms and mitochondrial localization

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2019-11, Vol.8

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Clusterin (CLU), or apolipoprotein J (ApoJ), is the third most predominant genetic risk factor associated with late-onset Alzheimer's disease (LOAD). In this study, we use multiple rodent and human brain tissue and neural cell models to demonstrate that CLU is expressed as multiple isoforms that have distinct cellular or subcellular localizations i...

Alternative Titles

Full title

Brain clusterin protein isoforms and mitochondrial localization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cc6acdd30eb144ba92c144ec53ff6c43

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc6acdd30eb144ba92c144ec53ff6c43

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.48255

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