Targeted accumulation of selective anticancer depsipeptides by reconstructing the precursor supply i...
Targeted accumulation of selective anticancer depsipeptides by reconstructing the precursor supply in the neoantimycin biosynthetic pathway
About this item
Full title
Author / Creator
Zhou, Lin , Shen, Yaoyao , Chen, Nannan , Li, Wanlu , Lin, Hou-wen and Zhou, Yongjun
Publisher
Singapore: Springer Singapore
Journal title
Language
English
Formats
Publication information
Publisher
Singapore: Springer Singapore
Subjects
More information
Scope and Contents
Contents
Background
Neoantimycins are a group of 15-membered ring depsipeptides isolated from
Streptomycetes
with a broad-spectrum of anticancer activities. Neoantimycin biosynthesis is directed by the hybrid multimodular megaenzymes of non-ribosomal peptide synthetase and polyketide synthase. We previously discovered a new neoantimycin analogue un...
Alternative Titles
Full title
Targeted accumulation of selective anticancer depsipeptides by reconstructing the precursor supply in the neoantimycin biosynthetic pathway
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cc8c982441dc41f5b17a124dcffcafd7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc8c982441dc41f5b17a124dcffcafd7
Other Identifiers
ISSN
2197-4365
E-ISSN
2197-4365
DOI
10.1186/s40643-021-00397-z
