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Identification of candidate nsSNPs of the human FNDC5 gene and their structural and functional conse...

Identification of candidate nsSNPs of the human FNDC5 gene and their structural and functional conse...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc9ef0380e9941e794610699191ecf17

Identification of candidate nsSNPs of the human FNDC5 gene and their structural and functional consequences using in silico analysis

About this item

Full title

Identification of candidate nsSNPs of the human FNDC5 gene and their structural and functional consequences using in silico analysis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2025-03, Vol.15 (1), p.7681-14, Article 7681

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Fibronectin type-III domain containing protein-5 (FNDC5)
, predominantly expressed in skeletal muscles, encodes FNDC5 transmembrane-protein. A segment of this protein is cleaved and secreted into blood as irisin, which promotes browning of white adipose tissue, leading to energy expenditure. It functions synergistically with fibroblast growth fa...

Alternative Titles

Full title

Identification of candidate nsSNPs of the human FNDC5 gene and their structural and functional consequences using in silico analysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cc9ef0380e9941e794610699191ecf17

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc9ef0380e9941e794610699191ecf17

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-83254-1

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