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Spatial transcriptomics reveals substantial heterogeneity in triple-negative breast cancer with pote...

Spatial transcriptomics reveals substantial heterogeneity in triple-negative breast cancer with pote...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ccc6eec04dde4ff3a3fd0330c0c3eaf5

Spatial transcriptomics reveals substantial heterogeneity in triple-negative breast cancer with potential clinical implications

About this item

Full title

Spatial transcriptomics reveals substantial heterogeneity in triple-negative breast cancer with potential clinical implications

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-11, Vol.15 (1), p.10232-22, Article 10232

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

While triple-negative breast cancer (TNBC) is known to be heterogeneous at the genomic and transcriptomic levels, spatial information on tumor organization and cell composition is still lacking. Here, we investigate TNBC tumor architecture including its microenvironment using spatial transcriptomics on a series of 92 patients. We perform an in-dept...

Alternative Titles

Full title

Spatial transcriptomics reveals substantial heterogeneity in triple-negative breast cancer with potential clinical implications

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ccc6eec04dde4ff3a3fd0330c0c3eaf5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ccc6eec04dde4ff3a3fd0330c0c3eaf5

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-54145-w

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