Evolutionary instability of CUG-Leu in the genetic code of budding yeasts
Evolutionary instability of CUG-Leu in the genetic code of budding yeasts
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Author / Creator
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States) , Univ. of Wisconsin, Madison, WI (United States) , Krassowski, Tadeusz , Coughlan, Aisling Y. , Shen, Xing-Xing , Zhou, Xiaofan , Kominek, Jacek , Opulente, Dana A. , Riley, Robert , Grigoriev, Igor V. , Maheshwari, Nikunj , Shields, Denis C. , Kurtzman, Cletus P. , Hittinger, Chris Todd , Rokas, Antonis and Wolfe, Kenneth H.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The genetic code used in nuclear genes is almost universal, but here we report that it changed three times in parallel during the evolution of budding yeasts. All three changes were reassignments of the codon CUG, which is translated as serine (in 2 yeast clades), alanine (1 clade), or the ‘universal’ leucine (2 clades). The newly discovered Ser2 c...
Alternative Titles
Full title
Evolutionary instability of CUG-Leu in the genetic code of budding yeasts
Authors, Artists and Contributors
Author / Creator
Univ. of Wisconsin, Madison, WI (United States)
Krassowski, Tadeusz
Coughlan, Aisling Y.
Shen, Xing-Xing
Zhou, Xiaofan
Kominek, Jacek
Opulente, Dana A.
Riley, Robert
Grigoriev, Igor V.
Maheshwari, Nikunj
Shields, Denis C.
Kurtzman, Cletus P.
Hittinger, Chris Todd
Rokas, Antonis
Wolfe, Kenneth H.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cced401e48ce421aa4209a2b5302837c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cced401e48ce421aa4209a2b5302837c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04374-7
