Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis
Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis
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Author / Creator
Dai, Bingyang , Xu, Jiankun , Li, Xu , Huang, Le , Hopkins, Chelsea , Wang, Honglian , Yao, Hao , Mi, Jie , Zheng, Lizhen , Wang, Jiali , Tong, Wenxue , Chow, Dick Ho-kiu , Li, Ye , He, Xuan , Hu, Peijie , Chen, Ziyi , Zu, Haiyue , Li, Yixuan , Yao, Yao , Jiang, Qing and Qin, Ling
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Epididymal white adipose tissue (eWAT) secretes an array of cytokines to regulate the metabolism of organs and tissues in high-fat diet (HFD)-induced obesity, but its effects on bone metabolism are not well understood. Here, we report that macrophages in eWAT are a main source of osteopontin, which selectively circulates to the bone marrow and prom...
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Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis
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TN_cdi_doaj_primary_oai_doaj_org_article_cd1861519b2b4fda9aee7ace3bf268b9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd1861519b2b4fda9aee7ace3bf268b9
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27683-w
