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DPD status and fluoropyrimidines-based treatment: high activity matters too

DPD status and fluoropyrimidines-based treatment: high activity matters too

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd4f48b432f14f5fbb39a2b8bb2cd237

DPD status and fluoropyrimidines-based treatment: high activity matters too

About this item

Full title

DPD status and fluoropyrimidines-based treatment: high activity matters too

Publisher

England: BioMed Central Ltd

Journal title

BMC cancer, 2020-05, Vol.20 (1), p.436-9, Article 436

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Dihydropyrimidine dehydrogenase (DPD) status is an indicator of a marked risk for toxicity following fluoropyrimidine (FP)-based chemotherapy. This notion is well-established for low DPD status but little is known about the clinical impact of high DPD activity. This study examined the possible link between high intrinsic lymphocytic DPD activity an...

Alternative Titles

Full title

DPD status and fluoropyrimidines-based treatment: high activity matters too

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cd4f48b432f14f5fbb39a2b8bb2cd237

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd4f48b432f14f5fbb39a2b8bb2cd237

Other Identifiers

ISSN

1471-2407

E-ISSN

1471-2407

DOI

10.1186/s12885-020-06907-0

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