Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet home...
Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis
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Author / Creator
Zhang, Qilun , Shen, Xuting , Yuan, Xin , Huang, Jing , Zhu, Yaling , Zhu, Tengteng , Zhang, Tao , Wu, Haibo , Wu, Qian , Fan, Yinguang , Ni, Jing , Meng, Leilei , He, Anyuan , Shi, Chaowei , Li, Hao , Hu, Qingsong , Wang, Jian , Chang, Cheng , Huang, Fan , Li, Fang , Chen, Meng , Liu, Anding , Ye, Shandong , Zheng, Mao and Fang, Haoshu
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Oxidative stress-induced lipid accumulation is mediated by lipid droplets (LDs) homeostasis, which sequester vulnerable unsaturated triglycerides into LDs to prevent further peroxidation. Here we identify the upregulation of lipopolysaccharide-binding protein (LBP) and its trafficking through LDs as a mechanism for modulating LD homeostasis in resp...
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Full title
Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis
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TN_cdi_doaj_primary_oai_doaj_org_article_cd628ea85d2a4584a3d193cdf6fe7360
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd628ea85d2a4584a3d193cdf6fe7360
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-47553-5
