In Vitro Study of Cytotoxic Mechanisms of Alkylphospholipids and Alkyltriazoles in Acute Lymphoblast...
In Vitro Study of Cytotoxic Mechanisms of Alkylphospholipids and Alkyltriazoles in Acute Lymphoblastic Leukemia Models
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Author / Creator
Jesus, Larissa de Oliveira Passos , de Souza, Aline Aparecida , Torquato, Heron Fernandes Vieira , Gontijo, Vanessa Silva , Pereira de Freitas, Rossimirian , Gesteira, Tarsis Ferreira , Coulson-Thomas, Vivien Jane , Torquato, Ricardo José Soares , Tanaka, Aparecida Sadae , Paredes-Gamero, Edgar Julian and Judice, Wagner Alves de Souza
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
This study investigates the efficacy of miltefosine, alkylphospholipid, and alkyltriazolederivative compounds against leukemia lineages. The cytotoxic effects and cellular and molecular mechanisms of the compounds were investigated. The inhibitory potential and mechanism of inhibition of cathepsins B and L, molecular docking simulation, molecular d...
Alternative Titles
Full title
In Vitro Study of Cytotoxic Mechanisms of Alkylphospholipids and Alkyltriazoles in Acute Lymphoblastic Leukemia Models
Authors, Artists and Contributors
Author / Creator
de Souza, Aline Aparecida
Torquato, Heron Fernandes Vieira
Gontijo, Vanessa Silva
Pereira de Freitas, Rossimirian
Gesteira, Tarsis Ferreira
Coulson-Thomas, Vivien Jane
Torquato, Ricardo José Soares
Tanaka, Aparecida Sadae
Paredes-Gamero, Edgar Julian
Judice, Wagner Alves de Souza
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cd7f56a88df14d13b6557e862685e763
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd7f56a88df14d13b6557e862685e763
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules27238633