The pediatric leukemia oncoprotein NUP98-KDM5A induces genomic instability that may facilitate malig...
The pediatric leukemia oncoprotein NUP98-KDM5A induces genomic instability that may facilitate malignant transformation
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Pediatric Acute Myeloid Leukemia (AML) is a rare and heterogeneous disease characterized by a high prevalence of gene fusions as driver mutations. Despite the improvement of survival in the last years, about 50% of patients still experience a relapse. It is not possible to improve prognosis only with further intensification of chemotherapy, as come...
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The pediatric leukemia oncoprotein NUP98-KDM5A induces genomic instability that may facilitate malignant transformation
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TN_cdi_doaj_primary_oai_doaj_org_article_cd8444ff40804d0bb9b17a413dfc920d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd8444ff40804d0bb9b17a413dfc920d
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-023-05870-5
