ETV4 promotes late development of prostatic intraepithelial neoplasia and cell proliferation through...
ETV4 promotes late development of prostatic intraepithelial neoplasia and cell proliferation through direct and p53-mediated downregulation of p21
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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ETV4 is one of the ETS proteins overexpressed in prostate cancer (PC) as a result of recurrent chromosomal translocations. In human prostate cell lines, ETV4 promotes migration, invasion, and proliferation; however, its role in PC has been unclear. In this study, we have explored the effects of ETV4 expression in the prostate in a novel transgenic...
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Full title
ETV4 promotes late development of prostatic intraepithelial neoplasia and cell proliferation through direct and p53-mediated downregulation of p21
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TN_cdi_doaj_primary_oai_doaj_org_article_cd8927592cdc49d7b78d2088888df621
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd8927592cdc49d7b78d2088888df621
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ISSN
1756-8722
E-ISSN
1756-8722
DOI
10.1186/s13045-020-00943-w
