Nanoparticle delivery of miR-21-3p sensitizes melanoma to anti-PD-1 immunotherapy by promoting ferro...
Nanoparticle delivery of miR-21-3p sensitizes melanoma to anti-PD-1 immunotherapy by promoting ferroptosis
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Author / Creator
Guo, Weinan , Wu, Zhenjie , Chen, Jianru , Guo, Sen , You, Weiming , Wang, Sijia , Ma, Jinyuan , Wang, Huina , Wang, Xiangxu , Wang, Hao , Ma, Jingjing , Yang, Yuqi , Tian, Yangzi , Shi, Qiong , Gao, Tianwen , Yi, Xiuli and Li, Chunying
Publisher
London: BMJ Publishing Group Ltd
Journal title
Language
English
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Publisher
London: BMJ Publishing Group Ltd
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Scope and Contents
Contents
BackgroundAlthough anti-programmed cell death protein 1 (PD-1) immunotherapy is greatly effective in melanoma treatment, low response rate and treatment resistance significantly hinder its efficacy. Tumor cell ferroptosis triggered by interferon (IFN)-γ that is derived from tumor-infiltrating CD8+ T cells greatly contributes to the effect of immuno...
Alternative Titles
Full title
Nanoparticle delivery of miR-21-3p sensitizes melanoma to anti-PD-1 immunotherapy by promoting ferroptosis
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cddcc949d9484abda1f7fef81ea20f4b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cddcc949d9484abda1f7fef81ea20f4b
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2021-004381
